mRNA Based Vaccine Tools
mRNA vaccines have emerged as a promising platform for rapid development and deployment against infectious diseases. These innovative vaccines offer unparalleled speed, flexibility, and safety compared to traditional vaccine platforms. Their success in combating COVID-19 has solidified their potential to tackle a broad spectrum of infectious diseases, including influenza, HIV, and emerging pathogens. Our comprehensive portfolio of reagents provides researchers with the essential tools to advance mRNA vaccine development, from antigen design to clinical trials.
Recent advancements further fuel the excitement surrounding mRNA vaccines. A study published in 2024 demonstrates the promise of self-amplifying mRNA (saRNA) technology. By encoding replication machinery within the mRNA itself, saRNA vaccines can induce a stronger immune response without the need for high initial doses, potentially leading to more efficient vaccination strategies.
This momentum extends beyond infectious diseases. Researchers are exploring the potential of mRNA vaccines for cancer immunotherapy, targeting specific tumor antigens to elicit potent anti-tumor responses.
Krishgen, via its principal partners offers a wide range of products for development and production of mRNA vaccines:
- Enzymes:
- Reverse transcriptase for cDNA synthesis
- RNA polymerases for in vitro transcription
- Endonucleases for mRNA modification and purification
- Ligases for mRNA assembly
- Capsids:
- Modified capsids for enhanced mRNA delivery and protection
- Self-assembling nanoparticles for mRNA encapsulation
- Delivery Systems:
- Lipid nanoparticle formulations for efficient mRNA delivery
- Electroporation devices for in vivo mRNA delivery
- Buffers and Reagents:
- Specialized buffers and reagents for mRNA synthesis, purification, and characterization
Enzymes, Polymerases and Buffers from Krishgen
Krishgen, already a leading manufacturer of ELISA kits, recently launched its own range of enzymes for mRNA research.
We offer:
- Restriction Enzymes
- In Vitro Transcription Reagents
- Post transcription modification reagents
DNA & RNA Purification Kits from ABM
The importance of efficient and reliable DNA and RNA extraction is required for a wide range of molecular biology applications. Our principal company ABM offers a variety of specialty DNA and RNA kits with optimized protocols for extracting nucleic acids from various sources, including animals, plants, blood, bacteria, and fungi. Whether you’re conducting routine molecular biology experiments or pursuing cutting-edge research, our kits provide the performance and value you need.
Additionally, you can find affordable and reliable kits for routine techniques such as miniprep plasmid extraction as well as gel and PCR clean up purification
Quality Control ELISA from Krishgen
One of the world’s first manufacturers of the dsRNA ELISA kit (J2 based), Krishgen works with companies globally for their quality control and contamination detection processes.
We manufacture:
- dsRNA ELISA (J2 and K1 based)
- DNAse and RNAse ELISA
- Host Cell Protein and DNA ELISA
Cutting-Edge Lipid Nanoparticles from Cayman Chemical
Cayman Chemical empowers researchers with a comprehensive portfolio of innovative lipid nanoparticles (LNPs) – the workhorse of mRNA delivery. Our pre-formulated and customizable LNPs offer unparalleled versatility and performance, allowing you to unlock the full potential of mRNA therapeutics.
Why Choose Cayman Chemical's Lipid Nanoparticles?
- Unmatched Versatility: Explore a wide range of pre-formulated LNPs optimized for various mRNA delivery applications.
- Customizable Solutions: Collaborate with our team to tailor LNPs to your specific mRNA delivery needs.
- High Quality and Purity: Benefit from rigorously tested LNPs ensuring consistent and reliable results.
LNP Products offered:
- Pre-formulated LNPs: Explore a diverse library of pre-formulated LNPs optimized for different mRNA delivery routes (e.g., intravenous, intranasal) and target tissues (e.g., liver, lung).
- Custom LNP Development: Partner with our team to design and develop LNPs tailored to your specific mRNA delivery requirements.
- LNP Components: Access a comprehensive selection of high-purity lipids and helper components for in-house LNP formulation.
