Substrates / Metabolites / Media and Other Reagents

At Krishgen Biosystems, we provide a comprehensive range of substrates, metabolites, media, and reagents that are critical for toxicology, pharmacology, and ADME research. Our curated product portfolio features top-tier offerings from BioIVT, Moltox, and ReadyCell, and others, each bringing unique capabilities to support your experimental needs. From specialized cell culture media to assay-ready kits and metabolic substrates, we are your trusted partner in achieving reliable and reproducible results.

Substrates and Metabolites

• Control (CYP) P450 Substrates
• Endogenous Metabolites
• Prodrugs and Precursors Inhibitors

Specialised Culture Media

• Co-culture Media
• Buffer Systems
• Solvent Systems

Co-Factors and Supplements

• NADPH Regeneration Systems
• UDPGA and PAPS
• Glutathione (GSH)

Plasma and Serum

• Normal Human Serum / Plasma
• Diseased Human Serum / Plasma
• Animal Serum and Plasma

Key Benefits:

  • Reagents and media are rigorously tested for consistency and accuracy

  • Meet regulatory standards for preclinical and drug development studies

  • Ready-to-use formats reduce variability and improve reproducibility

  • Comprehensive portfolio covering all stages of ADME/DMPK research, including absorption, metabolism, and transporter studies

  •  Optimized protocols streamline workflows and save valuable research time

  • Specialized co-culture systems and transporter-certified hepatocytes to mimic physiological conditions

Applications

Our substrates, metabolites, media, and reagents are ideal for:

  • Toxicology Studies: Assessing genotoxicity, cytotoxicity, and environmental toxicity.

  • Drug Development: Supporting ADME studies, transporter interactions, and metabolic profiling.

  • Pharmacokinetics: Investigating absorption, distribution, metabolism, and excretion pathways.

Looking for additional types of media and cell culture reagents? Browse our comprehensive catalog spanning 10+ supplier partners.

InVitroGRO™ Media by BioIVT

Elevate your hepatocyte and liver research with InVitroGRO™ Media, a specialized suite of products by BioIVT designed for optimal performance in primary hepatocyte applications. As a trusted partner, Krishgen Biosystems offers the complete range of InVitroGRO™ media, ensuring your research is supported with high-quality, reliable solutions.

1. InVitroGRO™ HI Media

Optimized for hepatocyte isolation, maintaining high cell viability during processing.

InVitroGRO™ CP Media

Cryopreservation media for hepatocytes, preserving cellular integrity and metabolic activity.

InVitroGRO™ KHB Media

Krebs-Henseleit buffer for short-term hepatocyte suspension studies.

InVitroGRO™ HT Media

Media tailored for hepatocyte plating, ensuring optimal attachment and morphology.

InVitroGRO™ HP Media

Specialized for post-plating hepatocyte maintenance, promoting long-term culture viability.

InVitroGRO™ HI-UP Media

o Advanced media for isolating and maintaining high-functioning hepatocyte suspensions.

Why Choose InVitroGRO™ Media?

  • Performance-Driven: Supports hepatocyte functionality, including metabolic and transporter activity.
  • Comprehensive Options: Covers all stages, from isolation to long-term maintenance.
  • Reliability: Backed by rigorous quality control to ensure consistent results.
  • Substrates
  • Metabolites
  • Chemicals
  • Serum / Plasma
  • Hepatocyte / Fibroblast Cell Media
  • Media Additives
  • Specialised Media
  • Specific Drug Substrates
  • Custom Supplements
  • NADPH Regeneration Systems
  • Enzymes
  • Substrates / Co-Factors
  • Inhibitors / Activators
  • Antibodies
  • Substrates
  • Enzyme Mixtures
  • Inhibitors / Activators
  • Enzymatic Activity Kits

Prefer testing at our lab? Reach out to our services team to learn more.