Host Cell DNA ELISA
Host Cell DNA ELISA is a critical analytical technique for biopharmaceutical and vaccine research and manufacturing. Cell lines used as expression systems inadvertently produce host cell DNA contaminants that can impact safety, efficacy, and quality of the final product. Although low levels of most contaminants may be inconsequential, patient safety importance requires that they be eliminated or reduced to the lowest levels to avoid problems such as adverse immune reactions.
Regulatory agencies enforce strict limits on HCP DNA levels to minimize potential immunogenic reactions and ensure product purity. Krishgen offers a comprehensive range of HCP DNA detection kits designed to address these concerns and empower you to develop safe and compliant biopharmaceuticals.
Why is HCP DNA Detection Crucial in Biopharmaceutical Manufacturing?
- Patient Safety: HCP DNA can trigger adverse immune responses in patients receiving biopharmaceuticals.
- Regulatory Compliance: Stringent regulations mandate the control of HCP DNA levels in biopharmaceuticals.
- Product Efficacy: Residual HCP DNA can interfere with the therapeutic activity of your biopharmaceutical product.
Accurately Detect Host Cell DNA Contamination with Krishgen
Krishgen’s range of sensitive Host cell DNA ELISA allow for accurate detection of these bioprocess contaminants. A brief list of ELISA includes kits for various host cell systems, designed to meet the diverse needs of biopharmaceutical researchers and manufacturers.
Our focus is on ensuring low intra-assay variability that allows for streamlined testing across production batches. Detect and quantify Host cell DNA concentrations at any point in your purification processes. Featured products include:
- Ecoli Host Cell DNA Kit: Designed for sensitive detection of HCP DNA from E. coli expression systems.
- Insect Cell Host Cell DNA Kit: Ideal for detecting HCP DNA contamination in products manufactured using insect cell lines.
