Liposomes

These are nanoscale vesicles made of lipid molecules. They are used in drug delivery systems to encapsulate and transport drugs to specific targets in the body, improving their effectiveness and reducing side effects.

Liposomes have the unique ability to cross the cell membrane due to their bilayer structure, which makes them useful for the delivery of certain medications and nutrients. The lipid will burst or break down when it reaches a particular predefined location in the body, delivering potentially life-saving medications.

 

Overcome Key Challenges in Advancing Liposome Formulations

With the in-depth development of liposome research, the preparation process has also been improved. The existing technology has been able to overcome various shortcomings in the preparation of liposome formulations before, and can achieve:

– Manufacturing conditions of reproducible liposomes

– Liposome particle size was controlled by instrument parameters

– The combination of drug loading and liposome one-step molding can achieve efficient and multifunctional drug loading

– Fast and easy liposome production and optimization

Advantages of Liposomal Drug Delivery System:

– Liposomes are particularly fascinating in the field of drug delivery because of their unique properties, including:

– By formulating them into liposomes as the drug carrier, many drugs can be stabilized.

– Liposomes are composed of naturally occurring substances, so they have the unique advantages of being non-toxic and biodegradable. When encapsulated by liposomes, it can protect biologically active substances from degradation. The drugs entrapped in liposomes will not be activated under physiological conditions and will not cause adverse side effects. The encapsulation of drugs in liposomes can promote the local delivery of drugs and increase the utilization rate through controlled release.

– As a system for drug delivery, liposomal dispersions may be beneficial through several mechanisms. They can dissolve water-insoluble drugs (such as minoxidil or amphotericin B), avoid the site and reduce toxicity by reducing absorption to sensitive tissues.

– Liposomes can preserve the drug intact and deliver it to the targeted site.

– They also enhance the ability of the drug to penetrate into the deepest layer of the skin.

– In addition to being a good carrier for other ingredients, liposomes themselves also have advantages because they can reduce skin dryness (emollient properties).

– They stabilize the hydrolysis and oxidation of drugs.

– The liposome emulsion has low immunogenicity.

We have strong and extensive expertise and years of experience in the field of drug delivery and lipid biophysics. For more details about liposome products. Connect with us at sales@krishgen.com