Integral Molecular
Integral Molecular is an experienced provider of pseudoviruses, virus-like particles, and other virology products. Our products are critical reagents that expedite development of vaccines and antiviral therapeutics. Our ever-growing catalog supports scientists in the fight against diverse viruses, including influenza, SARS-CoV-2, dengue, Zika, Chukungunya, Ebola, Marburg, Nipah, and more.
Our flagship product is Reporter Virus Particles (RVPs). These non-replicative particles are a safe, ready-to-use substitute for live virus. RVPs are ideal for infectivity and neutralization assays.
Over 100 labs worldwide have used our virology reagents in testing the efficacy of vaccines and therapeutics. The results appear in 114 (and counting) publications and patents.
When you order Integral Molecular’s products, you get more than a reagent. You also receive optimized protocols and technical support—all backed by the highest quality standards and 20+ years of expertise.
Featured Products
- SARS-CoV-2, XBB.1.5 Reporter Virus Particle (RVP-786) – A non-replicative, ready-to-use pseudovirus for the latest COVID-19 vaccine strain
- Zika Reporter Virus Particle (RVP-601) – A non-replicative, ready-to-use virus-like particle for your Zika neutralization assay
- Dengue, Serotype 1 Reporter Virus Particle (RVP-101) – A non-replicative, ready-to-use virus-like particle for your Dengue neutralization assay
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SHOTGUN MUTAGENESIS EPITOPE MAPPING SERVICES
High-resolution epitope mapping with >95% success, even for complex proteins and conformational epitopes
How will epitope data help you?
High-resolution epitope mapping enables
1) lead candidate selection by uncovering mechanisms of action.
2) MAb protection by strengthening IP.
A high-throughput platform for enhancing any protein: antibodies, viruses, membrane proteins, fusion proteins, and more
The Most Versatile Protein Engineering Platform in the Industry Do you want your protein to work better? Using our high-throughput engineering platform, we make hundreds of variants of any protein expressed from a human cell line – antibodies, viruses, enzymes, cytokines, and more. You get ready-to-use protein variants expressed from human cells ready for testing in your assay, and your team’s time is free for other work.
Protein engineering offers a systematic approach to generating protein variants with improved characteristics — e.g. higher affinity, greater stability, or increased enzymatic activity. But proteins are complex, and it’s difficult to predict which mutations will produce the desired outcome, even with structural analysis and AI predictions. Ultimately, variants must be expressed and tested— often in human cells, which many proteins require for proper folding, post-translational modifications, and biological activity.
The Krishgen support team strives to provide swift responses and
resolution to your queries.