Fetal Bovine Serum and Alternates

Fetal bovine serum (FBS) remains a cornerstone of cell culture, providing essential nutrients, growth factors, and hormones that support cell growth, proliferation, and differentiation. However, concerns about batch-to-batch variability, ethical considerations, and the risk of contamination have led researchers to explore alternative options.

Krishgen’s partners offer FBS from:

  • South America
  • Australia
  • United States
  • Uruguay
  • Mexico
  • Dominican Republic
  • Japan

The composition of FBS is complex and varies based on factors such as geographic origin, processing methods, and ethical considerations. Key factors to consider:

  • Sterility: Free from contamination to protect your cell cultures.
  • Mycoplasma-Free: Guaranteed to be free from mycoplasma contamination.
  • Viral Inactivation: Treated to remove potential viral contaminants.
  • Consistency: Rigorous quality control measures to minimize batch-to-batch variations.

Despite its widespread use however, concerns related to FBS sourcing and ethical considerations have prompted researchers to explore alternative options such as serum-free media formulations or defined sera. These alternatives aim to provide a more controlled and scalable approach to cell culture while addressing the limitations and ethical concerns associated with traditional FBS usage.

 

At Krishgen, we offer a comprehensive range of bio sera products from various principal partners companies, including premium FBS and innovative alternatives, to cater to your diverse cell culture needs. Our commitment to quality and consistency ensures that you have access to the best possible options for your research.

Optimize Cell Growth, Function, and Reproducibility with Gemini Bio FBS

GeminiBio offers a wide range of FBS quality options – manufactured under cGMP – with complimentary samples, lot reservation, heat inactivation, and cold storage to improve customer’s workflow productivity, reproducibility, and speed. 

Their product portfolio spans US and USDA sourced FBS, as well as specialty FBS products such as stem cell qualified, insect cell qualified, dialyzed, as well as other options.

Why Choose Gemini Bio’s FBS?

  • Unmatched Quality: Gemini Bio FBS undergoes rigorous testing and quality control measures to guarantee sterility, mycoplasma-free status, viral inactivation, and minimal endotoxin levels.
  • Exceptional Performance: Experience consistently high cell viability, proliferation, and functionality across various cell types.
  • Enhanced Reproducibility: Minimize batch-to-batch variations with stringent quality control protocols, leading to reliable and reproducible results.
  • Ethical Sourcing: Prioritized ethical practices and collaborate with suppliers who adhere to the highest ethical standards.
  • Diverse Options: Explore the range of FBS products, including:
    • Standard FBS: Our most versatile option for a wide variety of cell culture applications.
    • Heat-Inactivated FBS: Inactivated to inactivate complement activity and minimize potential variations.
    • Charcoal-Stripped FBS: Depleted of hormones and other high-molecular weight components for specific research needs.

Cell Specific FBS from Pan Biotech

PAN-Biotech is a leading biotechnology company based in Aidenbach, Germany. They specialize in providing a wide range of high-quality reagents, media, and buffers for various life science research applications.

Pan Biotech offers specialized FBS formulations designed to support specific cell lines and primary cells, optimizing their growth and function. Explore their collection of:

 

  • Neuronal Cell-Specific FBS: Formulated to enhance the growth and differentiation of neuronal cells.
  • Epithelial Cell-Specific FBS: Specially designed to support the growth and function of epithelial cells.
  • Stem Cell-Specific FBS: Optimized for maintaining the pluripotency and expansion of stem cells.

Introducing an Animal Free FBS Alternate from PL Bioscience

PL Bioscience’s ELAREM™ platform is a portfolio of cell culture media based on human platelets. Due to their high growth factor content, human platelets are rich in nutrients necessary for in vitro cell expansion. The solution that extracts these relevant factors out of human platelets is called human Platelet Lysate.

All ELAREM™ products are xeno-free cell culture supplements. This means that the cell culture supplements and potential related products do not contain any animal components.

Elarem technology departs from traditional serum-containing media, instead utilizing a defined media formulation. This approach offers several distinct advantages:

  • Enhanced Consistency and Reproducibility: Defined media eliminates the inherent variability associated with serum, leading to consistent and reproducible research outcomes.
  • Reduced Risk of Contamination: Defined media significantly minimizes the risk of contamination from undefined components present in serum.
  • Targeted Cell Culture Support: Defined media allows for the precise control and optimization of specific growth factors and other components, tailoring the environment to your specific cell type and research needs.