Animal-Free Sera and Media
In the ever-evolving landscape of scientific research, the demand for ethical and sustainable solutions has grown exponentially. As researchers, it is our responsibility to prioritize the welfare of animals and minimize our impact on the environment. This is why we are proud to introduce a comprehensive range of animal component-free cell culture reagents from our supplier partners, carefully designed to meet your research needs while upholding ethical standards.
Advantages of Using Animal-Free Cell Culture Reagents
Eliminates the need for animal-derived components: Contributes to ethical research practices and reduces the risk of zoonosis (diseases transmitted from animals to humans).
- Mitigates the risk of contamination: Reduces the potential for contamination with animal pathogens, ensuring cleaner and more reliable results.
- Enhances reproducibility: Animal-free reagents offer greater consistency and reproducibility due to their chemically defined nature, leading to more reliable research outcomes.
At Krishgen, we understand the significant impact that the choices we make today have on the future of scientific research. That’s why we have committed ourselves to partnering with companies from around the world manufacturing high-quality, animal-free alternatives that provide optimal performance without compromising on ethics or sustainability. By embracing animal-free cell culture reagents, you can be part of a growing movement dedicated to conducting research that respects both animal welfare and the environment.
Krishgen’s partners offering Animal-Free Media, Supplements, and Growth Factors. Browse the tables below to learn more and click through to our partners’ website for more details or get in touch with our technical team for support choosing the right products for you.
High Quality, Chemically-defined blood-free products from Invitria
| Product Name | Product Description |
|---|---|
| ITSE Animal-Free | ITSE Animal-Free® is a recombinant insulin and transferrin cell culture 100x media supplement. ITSE AF contains four components that are typically required for optimal cell growth in serum-free or reduced serum media. Insulin has cell signaling functions and promotes the uptake of glucose and amino acids. Transferrin is a universal source of iron for cells that is non-toxic carrier of iron and reduces the generation of toxic free-radicals and peroxide. Selenium is required for the activity of glutathione peroxidase, thioredoxin reductase, and other antioxidant enzymes. Ethanolamine is a phospholipid precursor that improves the performance of cells in serum-free media and is required for the growth of some cell types. |
| ITS AF | ITS Animal-Free™ is a recombinant insulin and transferrin 100x cell culture media supplement that is ideal for serum-free or reduced serum cell culture applications. Similar to ITSE, ITS AF contains three components that are typically required for optimal cell growth in serum-free or reduced serum media but lacks ethanolamine. |
| ITSE + A | ITSE + Albumin Animal-Free™ is a recombinant blood-free insulin transferrin albumin 100x cell culture media supplement that also contains selenium and ethanolamine. ITSE + Albumin is intended to reduce or replace FBS or human serum in cell culture media. |
Mesenchymal and Pluripotent Stem Cell Media from PanBiotech
| Product Name | Product Description |
|---|---|
| Panexin CD, Serum Replacement with Defined Components | Panexin CD is an innovative brand-new product, developed based on the current state of science and 15 years of experience in developing serum replacements. Compared to Pan Biotech’s other serum replacements, Panexin CD contains only chemically defined components. |
| Panexin CD, Serum Replacement with Defined Components | Panexin CD is an innovative brand-new product, developed based on the current state of science and 15 years of experience in developing serum replacements. Compared to Pan Biotech’s other serum replacements, Panexin CD contains only chemically defined components.  |
Mammalian and Insect specific Media from Sino Biological
1) HEK293 Media
| Product Name | Type | Product Description |
|---|---|---|
| M293CD1 | SMM 293-CD1 Expression Medium | Latest generation product for HEK293 cell suspension culture, transient protein expression, and lentiviral packaging |
| M293TII | SMM 293-TII Expression Medium | New-generation product for HEK293 cell suspension culture, transient protein expression, and lentiviral packaging |
| M293TI | SMM 293-TI Expression Medium | Primary product for HEK293 cell suspension culture, transient protein expression, and lentiviral packaging |
| M293-SUPI | SMS 293-SUPI supplement | Used in combination with culture medium (Cat#: M293CD1, M293TII, M293TI) and added after transfection to increase expression yields |
2) Insect Cell Culture Media
| Product Name | Type | Product Description |
|---|---|---|
| MSF-AF | SIM SF Animal-Component-Free Medium | Sf9/Sf21 cell culture, baculovirus packaging, and protein expression |
| MHF-AF | SIM HF Animal-Component-Free Medium | Hi-5 cell culture and protein expression |
| MCHOSI | SMM CHO-SI Expression Medium | CHO-K1 cell screening, culture, and stable protein expression in DHFR systems |
| MCHO-SUPI | SMS CHO-S-SUPI supplement | Used in combination with culture medium (Cat#: MCHOSI) to increase expression yields |
3) CHO Cell Culture Media
| Product Name | Type | Product Description |
|---|---|---|
| MCHOGSI | SMM CHO-GSI Expression Medium | CHO-K1 cell screening, culture, and stable protein expression in GS systems |
| MCHOGS-C3 | SMM CHOGS-C3 Expression Medium | CHO-K1 cell screening, culture, and stable protein expression in GS systems |
| MCHO-GS-SUPI | SMS CHO-GS-SUPI supplement | Used in combination with medium (Cat#: MCHOGSI, MCHOGS-C3) to increase expression yields |
4) Hybridoma Cell Culture Media
| Product Name | Type | Product Description |
|---|---|---|
| MCHOTII | SMM CHO-TII Expression Medium | CHO-S cell culture and transient protein expression |
| MCHOT3 | SMM CHOT3 Expression Medium | CHO-S cell culture and transient protein expression |
| MCHO-SUPA | SMS CHO-SUPA supplement | Used in combination with culture medium (Cat#: MCHOTII, MCHOT3) to increase expression yields |
| Product Name | Product Description |
|---|---|
| Fibroblast Medium | Fibroblast Medium-animal component free (FM-acf), when used with Fibroblast Growth Supplement-animal component free (FGS-acf, Cat #2372), is a complete medium designed for optimal growth of normal fibroblasts in vitro. It is a sterile, liquid medium which contains essential and non-essential amino acids, vitamins, organic and inorganic compounds, hormones, growth factors and trace minerals. The medium is HEPES and bicarbonate buffered and has a pH of 7.4 when equilibrated in an incubator with an atmosphere of 5% CO2/95% air. The medium is formulated (quantitatively and qualitatively) to provide an optimally balanced nutritional environment that selectively supports the growth of normal fibroblasts in vitro. |
| Keratinocyte Medium | Keratinocyte Medium-animal component free (KM-acf), when used with Keratinocyte Growth Supplement-animal component free (KGS-acf, Cat #2172), is a complete medium designed for optimal growth of normal keratinocytes in vitro. It is a sterile, liquid medium which contains essential and non-essential amino acids, vitamins, organic and inorganic compounds, hormones, growth factors and trace minerals. The medium is HEPES and bicarbonate buffered and has a pH of 7.4 when equilibrated in an incubator with an atmosphere of 5% CO2/95% air. The medium is formulated (quantitatively and qualitatively) to provide an optimally balanced nutritional environment that selectively supports the growth of normal keratinocytes in vitro. |
| HematoGro Medium | HematoGro Medium'Animal Component Free (HemGM-ACF), when used with HematoGro Supplement'Animal Component Free (HemGS-ACF, Cat #5562) is a complete medium designed for short-term maintenance of hematopoietic cells in vitro, including bone marrow mononuclear and peripheral blood cells. It is a sterile, liquid medium which contains essential and non-essential amino acids, vitamins, hormones, organic and inorganic compounds and recombinant human serum albumin. The medium is HEPES and bicarbonate buffered and has a pH of 7.4 when equilibrated in an incubator with an atmosphere of 5% CO2/95% air. This medium does not contain serum, growth factors, cytokines or animal-derived components. Supplementation with additional factors may be used to support the proliferation or differentiation of select cell subpopulations. |