Cell Biologics
Cell Biologics is a premier manufacturer of primary cultured cells and cell culture products. We provide a broad range more than 2000 of high-quality human and animal primary cells derived from normal or diseased tissues, including endothelial, epithelial cells, bone marrow cells, liver cells, tumor cells and stem cells, along with optimized cell culture media and other related products.
Cell Biologics was the first to develop a novel proprietary technology to culture mouse primary endothelial cells. These cells have been extremely beneficial for in vitro studies in areas such as vascular biology/diseases, blood brain barrier research, tumor angiogenesis research, drug targeting, as well as for a variety of other basic science research.
In addition to the Company’s commitment is providing high quality cells world-wide, we are also developing therapeutic platforms targeting inflammatory diseases and novel drug delivery systems for therapeutic biologics as well as molecular biology products.
The goal of our scientists and staff is to provide you with the best human and animal primary cells for your research needs and to provide customized solutions to your specific research problems. We guarantee high quality service.
Featured Products
- Human Primary Chondrocytes – Chondrocytes in vivo produce and maintain the extracellular matrix of the cartilage. In vitro, chondrocytes after serial passages as a monolayer culture have been documented to lose their phenotypic markers and become de-differentiated. Re-differentiation can be induced by culturing the cells in a 3-D culture system. These cells are useful in studying chondrocyte differentiation and effects of cytokines and growth factors on the maintenance of differentiated phenotype..
- Prigrow CI Medium – abm’s PriGrow Media Series for mammalian cell culture is composed of high-quality, specific formulations for optimal cell growth.
- Cas9 Nuclease NLS Protein (Lyophilized) – The Cas9 nuclease from the bacteria Streptococcus pyogenes, abbreviated spCas9, is the most commonly used Cas9 variant. The reason for spCas9 popularity is two-fold. First the spCas9 PAM sequence is 5’-NGG, which is highly abundant in the genome allowing virtually any gene to be targeted. The spCas9 enzyme also has on average a higher efficiency in vivo compared to other variants. Cas9 Nuclease NLS contains a SV40 T antigen nuclear localization sequence (NLS) on the C-terminus of the protein.
- EACH-1 Cells – EACH-1 Cells are novel extra-axial chordoma tumor cells which exhibit chromosomal aberrations, and are tumorigenic and can form colonies on soft agar. It may be used to facilitate studies on the development and treatment of the rare low grade malignant tumor.EACH-1 Cells are novel extra-axial chordoma tumor cells which exhibit chromosomal aberrations, and are tumorigenic and can form colonies on soft agar. It may be used to facilitate studies on the development and treatment of the rare low grade malignant tumor.
- Cas9 Nuclease NLS Protein (Lyophilized) – The Cas9 nuclease from the bacteria Streptococcus pyogenes, abbreviated spCas9, is the most commonly used Cas9 variant. The reason for spCas9 popularity is two-fold. First the spCas9 PAM sequence is 5’-NGG, which is highly abundant in the genome allowing virtually any gene to be targeted. The spCas9 enzyme also has on average a higher efficiency in vivo compared to other variants. Cas9 Nuclease NLS contains a SV40 T antigen nuclear localization sequence (NLS) on the C-terminus of the protein.
Product Categories
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Services
ATAC-SEQ, RNA-SEQ, MIRNA-SEQ, DNA-SEQ, CHIP-SEQ KITS AND SERVICE
Next Generation Sequencing Library generation Services
As sequencing output increases and experimental scales are growing, generating libraries for sequencing is often the rate-limiting step. Cell biologics provides a fully integrated service for construction of high quality next-generation sequencing libraries to facilitate obtaining better data quality and less sequencing errors. Our library preparation services include library QC, library quantification, et al. All our libraries are specifically designed and optimized for any Illumina platform, and are already indexed (have a barcode).
We are happy to discuss the options and protocols suitable for your specific research projects. We prepare standard sequencing libraries as well as many specialized libraries and can also help you with custom projects. At the moment we are offering:
ATAC-Seq Kits
RNA-Seq Kits
ChIP-Seq Kits
DNA-Seq Kits
miRNA-Seq Kits (microRNA)
Methyl-Seq Kits
RNA-SEQ METHYL-SEQ, CHIP-SEQ KITS AND SERVICE
Next Generation Sequencing Library generation Services
As sequencing output increases and experimental scales are growing, generating libraries for sequencing is often the rate-limiting step. Cell biologics provides a fully integrated service for construction of high quality next-generation sequencing libraries to facilitate obtaining better data quality and less sequencing errors. Our library preparation services include library QC, library quantification, et al. All our libraries are specifically designed and optimized for any Illumina platform, and are already indexed (have a barcode).
We are happy to discuss the options and protocols suitable for your specific research projects. We prepare standard sequencing libraries as well as many specialized libraries and can also help you with custom projects. At the moment we are offering:
ATAC-Seq Kits and Service
RNA-Seq Kits and Service
ChIP-Seq Kits and Service
DNA-Seq Kits and Service
miRNA-Seq Kits (microRNA)
10X-Genomics GemCode Service
Methyl-Seq Service
CRISPR CUSTOM SERVICE
Cell Biologics is pleased to introduce our CRISPR based gene editing service to produce a genetically modified cells. Our scientists are experts at performing gene editing with CRISPR.
The custom CRISPR service would generate iPSC-derived cells with targeted gene deletions in primary endothelial cells, diabetic cells or other cell types, such as deletions of
· eNOS,
· VEGFR2,
· Tie2,
· Hif1-alpha,
· Hif2-alpha,
· VE-cadherin,
· Beta-catenin,
· Rac,
· Rho,
· Cdc42
IPSC CUSTOM SERVICE
Cell Biologics provides custom services to our customers upon request.
If you have any special needs in human iPSCs derived lineage specific cells from primary cells, diabetic cells or other cell types:
· Mesenchymal Stem Cells,
· Endothelial Cells
· Smooth Muscle Cells,
· Osteoblasts,
· Chondrocytes,
· Adipocytes,
· Neurons,
· Astrocytes,
· Cardiomyocytes
Contact Us
The Krishgen support team strives to provide swift responses and resolution to your queries.