Dyes, Labels, Probes Conjugation Tools
At Krishgen Biosystems, we provide an exceptional range of dyes, labels, probes, and conjugation tools designed to enhance the sensitivity, precision, and versatility of your assays. These tools are essential for labeling and detection applications in life sciences, diagnostics, and therapeutic development.
Innovative Solutions for Accurate Detection
Our portfolio includes a variety of high-performance reagents that streamline assay development and biomolecular interactions. Whether you need fluorescent dyes for imaging, probes for molecular diagnostics, or conjugation kits for antibody labeling, our products are engineered for superior reliability and reproducibility.
- High Purity and Stability
- Broad Application Compatibility
- Easy-to-Use Conjugation Kits
- Customized Solutions
With Krishgen Biosystems, you gain access to cutting-edge tools that deliver precision and flexibility, empowering breakthroughs in research and diagnostics. Trust our products to bring clarity to complex biological systems.
AAT Bioquest is dedicated to advancing fluorescent dye technologies through continuous innovation and a forward-thinking approach to assay development. By integrating expertise across diverse fields, from chemistry and biology to informatics, we have pioneered a new generation of photometric probes that leverage colorimetric, fluorimetric, and luminescent technologies. Our team of passionate scientists and experts is committed to solving some of the most challenging issues in life science research, diagnostic R&D, and drug discovery.
With a global network of skilled distributors, AAT Bioquest delivers high-quality products and tailored services to a wide range of clients, from small research institutions to Fortune 500 companies. We specialize in providing advanced custom and catalog fluorescent dye technologies, reagents, and assay kits for applications in flow cytometry, microplate readers, and fluorescence microscopy.
Featured Products
- Actin
- Calcium
- DNA Gel Stains & GeliteTM
- PE & APC
- Transfection and TransfectaminTM
- iFluor® Dyes
AlphaThera was co-founded in 2016 by Dr. Andrew Tsourkas and Dr. James Hui.
Dr. Tsourkas, a Professor of Bioengineering and Head of the Targeted Imaging, Therapeutics and Nanomedicine (TITAN) lab at the University of Pennsylvania, initially focused on developing nanoparticles for imaging and treating diseases such as cancer, atherosclerosis, and autoimmune conditions. However, he encountered challenges in scaling up these nanoparticles and expanding their applications due to the inefficient attachment of targeting antibodies, which are often costly and limited in availability. To address this, Dr. Tsourkas set out to create new technologies that would not only enhance the efficiency of bioconjugation reactions but also provide better control over the orientation of antibodies on surfaces to maximize their activity.
Dr. James Hui, who joined Dr. Tsourkas’s lab as an M.D./Ph.D. student, led the development of the concept to use photoreactive antibody-binding domains for site-specific labeling of Immunoglobulin G (IgG) heavy chains.
Together, they developed the LASIC (Light Assisted Site-specific Conjugation) technology and the oYo-Link® reagent family. Recognizing the critical role of antibodies in biomedical research and the limitations of existing conjugation methods, Drs. Tsourkas and Hui saw the immense potential of oYo-Link® to assist scientists in achieving their research goals.
This vision led to the formation of AlphaThera, a company that has since grown to engage the commercial sector with a team of scientists and business leaders.
Featured Products
- oYo-Link® SureLight® PE
- oYo-Link® SureLight® APC
- oYo-Link® HRP
- oYo-Link® Oligo Custom
Columbia Biosciences is a biotechnology company specializing in the development and production of high-quality fluorescent labeling reagents and assays. These products are widely used in research fields such as flow cytometry, microscopy, and in vitro diagnostics.
Founded in 2007 and based in Frederick, Maryland, USA, Columbia Biosciences is committed to providing innovative solutions to researchers and diagnostic developers. The company focuses on delivering products that are user-friendly, highly sensitive, and cost-effective. Columbia Biosciences offers a broad range of products, including fluorophores, antibody conjugation kits, and assay development services, and has forged strong partnerships with leading researchers and diagnostic companies worldwide.
Columbia Biosciences is also a proud member of the Pivotal Scientific Limited Alliance.