High Yield Flasks
Whether testing pharmaceuticals, performing toxicology, or testing for drugs of abuse, Krishgen’s tools have proven to be indispensable tools for sample prep when using HPLC, GC, LC-MS, or GC-MS, methodologies.
High-yield cell culture flasks offer several advantages over reusable flasks:
- Optimized Surface Treatment: High-yield flasks are specifically designed with surface treatments that promote optimal cell attachment and spreading. This enhances cell growth and reduces the risk of cell detachment, which can be a common issue with reusable Erlenmeyer flasks.
- Improved Gas Exchange: High-yield flasks often incorporate features that enhance gas exchange, such as wider necks or vented caps. This ensures adequate oxygen and carbon dioxide exchange for optimal cell growth and health.
- Uniform Nutrient Distribution: The design of high-yield flasks facilitates uniform nutrient distribution throughout the culture area, preventing nutrient gradients that can hinder cell growth and development.
- Reduced Contamination Risk: High-yield flasks are often disposable, which can help to reduce the risk of contamination compared to reusable Erlenmeyer flasks. Contamination can be a significant issue in cell culture, and using disposable flasks can minimize this risk.
The Foundation for Efficient Research from Thomson Instruments
Thomson offers a full line of shake flasks and accessories to help provide higher cell, protein and DNA yields. Shake Flasks are designed specifically for insect/mammalian, or microbial/E. coli based on an understanding and experience of lab operations.
Thomson’s high-yield cell culture flasks are engineered to optimize cell growth and proliferation, providing researchers with exceptional performance and productivity. Our innovative designs and premium materials ensure optimal cell attachment, nutrient exchange, and gas exchange, leading to enhanced cell yields and consistent results.
Featured Products from Thomson:
Shake Flasks
with higher working volumes and improved aeration increase efficiency for expansion of mammalian cells insect cells, E. coli and other microbial cells.
Transfer Caps
for seeding larger bags and fermenters as well as for filling flasks with media from a bulk source provide time and cost savings keeping your lab operations running smoothly
Specialty Shake Flasks
with multifunctional feed, transfer and sampling ports serve as mini-bioreactors reducing your media costs and save shaker space
Optimum Growth® System For Mammalian & Insect Cell Culture with 40-50% Fill Volume!
Thomson Optimum Growth® Flasks (patented) for mammalian and insect cell culture are much more efficient than traditional shake flasks due in part to the fact that they support a 40-50% fill volume versus 33% fill volume in traditional flasks.
Optimum Growth® Special Flasks were designed with the unique needs of small-to-medium-scale bioprocessing applications.
Ultra Yield® System
Thomson’s Ultra Yield® system has proven over the last decade to enhance the aeration of E. coli and other microbial cells. The flasks are designed to be either single-use or autoclaved up to 3x and feature a unique geometry that enhances gas exchange. AirOtop® Enhanced Seals and Vented Screw Caps feature a 0.2μm hydrophobic gas-permeable resealable barrier providing consistent gas exchange for the duration of your culture.
- Cultivation of Sf9 insect cells in Thomson Optimum Growth® flasks using ESF AdvanCD™ cell culture medium for production of SEAP and AAV
- Comparison of the Rapid Clear® Cap 3000 vs GE Capsule Filters for clarifying monospecific IgG
- From Strain Selection to Purification – Key Factors for Successful Plasmid Production
- Optimizing Plasmid Yields – Impact of Flask Design, Media Type and Shakingb Parameters
- Enhanced Plasmid Production: Achieving a 21-Fold Increase in Plasmids
- Improved DNA Protocol for *E.coli* with Plasmid+® Media
