Lectenz Bio
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Founded by glycoscientists passionate about innovation and accessibility, Lectenz Bio is dedicated to providing novel, effective, and affordable glyco-research and bioprocessing tools to our valued customers. Encompassing glycan detection, processing, and profiling, our product catalog is designed to make glycoscience simple! We maintain a strong, ever-evolving in-house Quality Management System, and all of our products undergo rigorous Quality Control testing.
Our flagship lectin-like, enzyme-derived Lectenz® reagents solve many of the issues often associated with other glycan detection reagents, while delivering consistent results. Compared to traditional lectins, Lectenz® are recombinant, monomeric, and available in native, biotinylated, and SureLight™ 488 labeled formats. Customers find our Lectenz® reagents particularly useful in applications such as western blotting, immunoprecipitation, immunohistochemistry, ELISA, and flow cytometry.
If you are interested in glycan modification or release, we also offer a wide range of quality, reliable enzymes at some of the best prices available. These include general glycan release enzymes, such as PNGase F and PNGase F-II, as well as various specialized enzymes for your glyco needs.
For those wanting to simplify their glycan analysis workflow, our multiplex bead-based flow cytometry kit, GlycoSense™, provides simple, near real-time terminal glycan profiling and excels where more complex methods are neither needed nor practical.
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Featured Products
- SiaFind™ Pan-Specific Lectenz® Kit – This reagent is a highly purified recombinant protein designed for the robust detection, separation, or enrichment of sialoglycans terminating in Siaα2,3Gal, Siaα2,6Gal, and Siaα2,8Sia commonly found in glycoconjugates (glycoproteins, glycolipids, and oligo- or polysaccharides).
- SiaFind™ α2,3-Specific Lectenz® Kit – This reagent is a highly purified recombinant protein designed for the detection, separation, or enrichment of sialoglycans terminating in Neu5Acα2,3Gal commonly found in glycoconjugates (glycoproteins, glycolipids, and oligo- or polysaccharides).
- SiaFind™ α2,6-Specific Reagent Kit – This reagent engineered from PSL lectin is a highly purified recombinant protein designed for sensitive, robust, and specific detection of Siaα2,6Gal commonly found in glycoconjugates (glycoproteins, glycolipids, and oligo- or polysaccharides).
- SiaFind™ Linkage Profiling Kit – This kit contains three SiaFind™ reagents and Pan Sialidase, for the detection, differentiation, or enrichment of sialoglycans.
- PNGase F – This enzyme catalyzes the cleavage of asparagine-linked oligosaccharides, except those containing an α1,3-linked core fucose, from glycoproteins and glycopeptides.
- GlycoSense™ Array Kit – This is a multiplex bead-based assay for the detection of glycosylation patterns on glycoproteins using a two-laser flow cytometer.
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SiaFind™ Characterization
Our SiaFind™ reagents maximize sialic acid research potential in many areas where traditional reagents might prove ineffective. Utilizing the strengths of our reagents, we can provide clients with data from western blots, immunohistochemistry, ELISA, flow cytometry, or biolayer interferometry.
SiaRich™ Chromatography
Our α2,3-Specific Column can enrich for glycoproteins containing α2,3-linked sialic acid. We can optimize method development for glycoproteins of interest and transfer the knowledge to our clients.
GlycoSense™ GlycoPrint
Using our novel GlycoSense™ kit, we are able to provide a simplified GlycoPrint of a glycoprotein, detecting the key terminal glycan monosaccharides sialic acid, galactose, and N-acetylglucosamine (GlcNAc). This is good value for clients who do not require detailed glycoforms because such techniques can be costly and have a long turnaround time. Clients can expect methods, results, and analysis that allows for independent GlycoSense™ use should they want to implement it themselves.
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