Leukopaks
Leukopaks are enriched leukapheresis products containing high concentrations of peripheral blood mononuclear cells (PBMCs), including T cells, B cells, NK cells, monocytes, and dendritic cells. These high-yield cell products are essential for a range of cell therapy, gene therapy, immunotherapy, and regenerative medicine applications.
Leukopaks Offered from BioIVT
Features & Benefits of BioIVT Leukopaks
Krishgen Biosystems offers high-quality cryopreserved Leukopaks from BioIVT, providing researchers with a reliable and standardized source of peripheral blood mononuclear cells (PBMCs). These Leukopaks deliver a higher purity of PBMCs compared to whole blood, with an increased mononuclear cell content from a single donor. Collected using the Spectra Optia Apheresis System with ACD-A anticoagulant, they ensure excellent cell viability and recovery.
- High Cell Yield & Viability – Large-volume collection ensures high PBMC and T cell recovery with exceptional post-thaw viability.
- Comprehensive Donor Screening – Collected from IRB-approved, consented donors under strict regulatory guidelines.
- Fresh & Cryopreserved Options – Available in cryopreserved format to maintain integrity and quality.
- Disease-State and Healthy Donors – Access to a diverse donor pool, including autoimmune, oncology, and inflammatory disease samples.
- GMP-Grade Availability – Suitable for research and translational studies with GMP-compliant options.
Partner Brands & Quality Assurance
BioIVT
A global leader in biospecimens, BioIVT provides high-quality Leukopaks for cell therapy research:
✔ Normal, mobilized, and disease-state Leukopaks
✔ High-yield PBMCs for immunology, oncology, and regenerative medicine
✔ Offers testing for various key viruses
Quality Assurance
BioIVT ensures consistency and reliability with strict quality controls.:
✔ IRB-approved donor screening for ethical sourcing
✔ Collected via Spectra Optia Apheresis System for optimal purity and viability
✔ Full traceability and regulatory documentation
Frozen Leukopaks Offered in India
Leukopaks are enriched leukocyte products collected via leukapheresis, offering high cell yield for research and cell therapy applications. Our range of frozen and mobilized Leukopaks provides flexibility and consistency for your studies.
Normal Leukopaks are collected from healthy donors and contain a rich mixture of PBMCs, including T cells, B cells, NK cells, and monocytes. They serve as a foundational resource for immunology research, assay development, and therapeutic studies.
Benefits:
- High Cell Yield – Provides a substantial number of viable cells for various assays.
- Consistency – Sourced from screened healthy donors to ensure reproducibility.
- Versatility – Applicable in multiple research areas, including immunology and drug development.
- Purity – High percentage of lymphocytes with minimal contamination.
- Viability – Maintains cell functionality post-thawing.
- Customization – Options for donor selection based on specific research needs.
Characterization Data:
- Cell Composition – Typically includes 57% T cells, 20% monocytes, 10% B cells, 7.5% NK cells, and 0.3% CD34+ stem cells. Available to customise.
Disease State Leukopaks are obtained from donors diagnosed with specific medical conditions, providing researchers with relevant cellular models to study disease mechanisms, biomarker discovery, and therapeutic development.
Available Products:
• Autoimmune Disorders: e.g., rheumatoid arthritis, lupus.
• Infectious Diseases: e.g., HIV, hepatitis.
Key features:
• Detailed Donor Profiles: Comprehensive medical histories accompany each Leukopak.
• Consistency: Single-donor sourcing minimizes variability.
• Customization: Tailored collections based on specific disease criteria.
Characterization Data:
• HLA Typing: Available to match research requirements.
• Cell Viability: Approximately 97% pre-freeze viability.
VivoStart (GMP) Leukopaks are collected under stringent Good Manufacturing Practice conditions, ensuring they meet regulatory standards for clinical applications, including cell and gene therapy manufacturing.
Available Products:
- Standard VivoStart: Balanced PBMC composition for general use, as well as Premier GMP grade Leukopaks which have additional viral testing data available
- Customizable Options: Donor selection based on HLA type, demographics, or health status.
Benefits:
- Regulatory Compliance: Meets GMP standards, facilitating seamless transition from research to clinical phases.
- Quality Assurance: Comprehensive testing ensures product integrity and safety.
- Scalability: Suitable for large-scale manufacturing processes.
Description: Mobilized Leukopaks are collected from donors treated with mobilizing agents, such as G-CSF, to increase the number of circulating hematopoietic stem cells (HSCs). These Leukopaks are ideal for stem cell research, gene therapy, and regenerative medicine applications.
Available Products:
- Mobilized LEUKOMAX® Leukopak – Provides a high yield of mobilized HSCs suitable for various research applications
- REF-iPSC – Rat Embryonic Fibroblast-derived iPSC
- SFFV-OCT4 SOX2 MEF-iPSC – Mouse Embryonic Fibroblast-derived iPSC with SFFV-OCT4 and SOX2 expression