Media and Supplements
The success of cell and gene therapy (CGT) hinges on the quality of c ell culture media and
supplements used throughout research, development, and manufacturing. From serum-free
and animal-free supplements to growth factors and cytokines, selecting the right reagents
ensures optimal cell expansion, differentiation, and viability for therapeutic applications.
At Krishgen Biosystems, we offer a curated portfolio of CGT-specific media and
supplements from InVitria, BioIVT, Sino Biological, and Gemini Bio, covering all aspects of
cell expansion, stem cell maintenance, and viral vector production.
Products Offered
Key Benefits of Our Media & Supplements
✔ Optimized for Cell & Gene Therapy – Ensures consistent, reproducible results in stem cells, T cells, and primary cell cultures.
✔ Animal-Free & GMP-Grade Solutions – Reduces batch-to-batch variability and ensures regulatory compliance.
✔ High Purity, Low Endotoxin – Suitable for clinical and preclinical CGT applications.
✔ Scalable from Research to Manufacturing – Supports process development and commercial bioproduction.
Partner Brands & Quality Assurance
Our Trusted Partners
InVitria – Animal-Free Supplements for CGT
✔ Serum-Free & Recombinant Solutions – Eliminates animal-derived variability, ensuring consistency and scalability in CGT workflows.
✔ cGMP-Grade Manufacturing – Products manufactured in ISO-certified, GMP-compliant facilities for clinical and commercial applications.
✔ Proven Performance – Widely used in stem cell culture, immune cell therapy, and viral vector production.
Gemini Bio – High-Quality Serum & Media Solutions
Premium FBS & Serum-Free Alternatives – Stringently tested FBS, human serum, and chemically defined media for CGT applications.
✔ Regulatory-Approved Manufacturing – Meets stringent endotoxin, sterility, and virus-testing standards for clinical and research use.
✔ Reliable & Scalable – Supports large-scale cell culture and CGT workflows with consistent quality.
Detailed Product Categories & Available Media & Supplements
Serum-free media components enhance consistency, safety, and scalability in CGT manufacturing.
InVitria provides serum-free and recombinant solutions that eliminate animal-derived variability, ensuring consistency and scalability in CGT workflows.
Their products are manufactured in ISO-certified, GMP-compliant facilities, making them suitable for both clinical and commercial applications. With a strong track record in stem cell culture, immune cell therapy, and viral vector production, InVitria’s supplements are widely used to enhance reliability and performance in cell and gene therapy.
Available Products:
- Cellastim S® (InVitria) – Recombinant human albumin, replacing BSA in serum-free media.
- Optiferrin® (InVitria) – Recombinant transferrin for enhanced cell growth and viral vector production.
- ITS, ITSE, ITSE+A Supplements (InVitria) – Serum-free Insulin-Transferrin-Selenium solutions.
🔗 [View Serum-Free Supplements]
FBS remains a critical supplement for many cell types, though serum-free alternatives are gaining adoption.
Available Products:
- Premium FBS (Gemini Bio) – Sterility-tested, low-endotoxin FBS.
- Serum-Free Alternatives – For consistent CGT applications.
🔗 [View FBS & Serum-Free Media Options]
Sino Biological’s recombinant cytokines and growth factors are produced using optimized expression systems, ensuring high bioactivity, lot-to-lot consistency, and minimal contaminants.
With both GMP-compliant cytokines for clinical and translational research and RUO cytokines for early-stage studies, Sino Biological provides high-quality reagents for CGT applications.
These growth factors and cytokines are specifically designed for T-cell expansion in CAR-T and TCR-T therapies, stem cell differentiation, and immune modulation, making them ideal for supporting cell and gene therapy workflows from research to manufacturing.
Available Products:
- IL-2, IL-7, IL-15, IL-21 (Sino Biological) – For T-cell activation and CAR-T expansion.
- EGF, FGF, VEGF (Sino Biological) – For stem cell maintenance and differentiation.
- GMP-Grade Cytokines – High-purity, low-endotoxin cytokines for CGT applications.
🔗 [View Recombinant Cytokines & Growth Factors]
Leukemia Inhibitory Factor (LIF) is a crucial cytokine widely used in stem cell culture, regenerative medicine, and cell and gene therapy (CGT). It plays a significant role in maintaining pluripotency, preventing spontaneous differentiation, and enhancing cell viability in a feeder-free environment.
- Animal-Free, Recombinant LIF – Produced using a serum-free, animal-free expression system, ensuring superior safety, consistency, and purity.
- Maintains Pluripotency – Supports long-term self-renewal of mouse embryonic stem cells (mESCs) and human pluripotent stem cells (hPSCs).
- Feeder-Free Compatible – Eliminates the need for traditional MEF feeder cells, streamlining workflows and improving reproducibility.
- Ultra-Pure & Low Endotoxin – Reduces unwanted immune responses and ensures optimal cell growth conditions.
🔗 [Explore LIF for Stem Cell Culture]
📞 Need Assistance? Contact Us!
✔ Expert Support: Get assistance with media selection, optimization, and scaling.
✔ Custom Solutions: Tailored supplements and formulations for CGT workflows.
✔ Regulatory Documentation Available: CoA, MSDS, and sterility testing reports included.
📩 [Contact Us for Pricing & Availability]